F.species.Report.html DSKM.html4/12/97 KS Updated 25/02/01 Dansk_tekst.html Besvarelse.html

Species

Antibiotic

S(1)____________I____________R(0)

Comment

 

S. aureus

S. aureus

S. aureus

 

Micrococcaceae, others

 

Str. pneumoniae

 

Erysipelothrix rhusiopathiae

-

Enterococcus

 

Enterococcus

 

Enterococcus

 

Enterococcus

 

 

 

 

N. meningitidis

N. gonorrhoeae

 

N. gonorrhoeae

Branhamella(Moraxella)

H. influenzae

-

-

-

-

-

Clostridium

-

-

-

-

Propionibacterium

-

Actinomyces

Bacteroides

 -

 -

 -

 -

B.fragilis

Peptostreptococcus

 

 

 

 

 

 

 

benzylpenicillin

methicillin

methicillin

 

methicillin

 

benzylpenicillin

 

penicillin

vancomycin

ampicillin

 

vancomycin

 

vancomycin

 

aminoglycosides

 

 

 

 

penicillin

penicillin

 

penicillin and ampicillin

ampicillin

ampicillin

ampicillin

penicillin G

penicillin V

chloramphenicol

ciprofloxacin

penicillin

piperacillin

methicillin

metronidazole

carbapenem

penicillin

metronidazole

metronidazole

penicillin

piperacillin

piperac+clavulanic acid

metronidazole

tetracycline

chloramphenicol

carbapenem

penicillin

methicillin

yes____________no____________yes

yes____________no____________yes

-______________no____________yes

 

yes____________no____________yes

 

yes_________0.1-1 mg/l_____>2 mg/l

 

yes____________no____________no

no_____________no____________yes

yes____________no____________yes

 

yes____________no____________yes

 

-___________4-8 mg/l__________yes

 

yes____________no____________yes

combined with

penicillin,

ampicillin or

vancomycin

yes__________0.1-1 mg/l________no

yes____________no____________yes

 

-___________0.1-1 mg/l_________yes

yes____________no____________yes

yes____________no____________yes

yes__________E-test___________yes

yes____________no____________yes

no____________yes____________yes

yes____________no____________yes

yes____________?_____________yes

yes____________no____________no

yes____________no____________no

yes____________no____________no

yes____________no____________no

yes____________no____________no

yes____________no____________no

no_____________no____________yes

yes____________no____________yes

yes____________no____________yes

yes____________no____________yes

yes____________no____________no

yes____________no____________no

yes____________no____________no

yes____________no____________no

yes____________no____________yes

yes____________no____________no

yes____________no____________yes

 

 

 

 

 

 

 broth agar with >5% NaCl (L 2)

methicillinase-producer,

borderline resistant (L 3,4)

as S.aureus, but read after 42 h

at <35oC (L 3,6)

discussion of treatment,

report of MIC (L 7,8)

 

(L 21)

screening with carbenicillin

and E-test.

VanA MIC >64 mg/l, also

teicopl.-R (L 9).

VanB MIC > 4 mg/l,

teicoplanin-S (L 10)

 

 

 

 

 

Clinically important? (L20,21,29)

Screen with oxacillin 1 microg

and Minibact N; E-test.

ß-lactamase negative.

Minibact N(B-lactamase)

ß-lactamase +, cephalothin-S

ß -lactamase -, cephalothin-R

as above

as above

 

unsettled (L 11)

 

 

 

 

 

(L 21)

 

 (L 12)

ß -lactamase test (L 13)

as above

 

 

 

 

Metallo- ß -lactamase (L 14)

 

nota bene

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Enterobacteriaceae(L 15,16)

Grouped as in D1.B-lactam.497.html

Group 1

S, sensitive (no R-traits): E.coli,

P. mirabilis, Salmonella, Shigella

 

Group 2., Inducible

cephalosporinase producers:

E.cloacae, Serratia etc.

 

Group 2.b. Mutated cephalospor-

inase producers: E.cloacae

 

 

Group 3.

Chromosomal

Penase-producers: Klebsiella

 

Group 4.

Y.enterocolitica

 

 

 

Group 5. Episomal

ß -lactamase-producers

TEM-1,TEM-2,SHV-1

 

 

 

Group 6. Extended spectrum

ß-lactamases. CTX-1,TEM-3,

TEM-4,, SHV-2

 

 

 

Ampicillin

carboxipenicillin

cephalosporin

 

ampicillin

carboxipenicillin

cephalosporin

 

ampicillin

carboxipenicillin

cephalosporin

mecillinam

 

ampicillin

carboxipenicillin

cephalosporin

 

ampicillin

carboxipenicillin

cephalothin

cefotaxime,aztreonam

 

 ampicillin

carboxipenicillin

cephalosporin

 

 

ampicillin

carboxipenicillin

cephalosporin

cephalosporin+clavul. acid

 

ceftazidime+aztreonam

 

 

 

yes________E.coli___________no

yes__________no____________no

yes______cephalothin_______no

 

no__________no____________yes

yes_________no____________no

no__________no____________yes

 

no__________no____________yes

no__________no____________yes

no__________no____________yes

yes_________no____________no

 

no__________no____________yes

no__________no__________yes

yes_________no____________no

 

no__________no____________yes

no__________no____________yes

no__________no____________yes

yes_________no_____________no

 

 no__________no__________yes

no__________no____________yes

yes_________no____________no

 

 

no__________no____________yes

no__________no____________yes

no__________no____________yes

yes_________no____________no

 

no__________no____________yes

 

 

 

 

 

 

 E.coli MIC < 8 mg/l

 

E.coli MIC50 = 16 mg/l

 

 

 

 

 

 

 

 

 

 

See table D1.B-lactam.497.html, footnote 2.

 

 

 

( L 25) 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

SHV-3,TEM-6,TEM-8 (L 23,28)

 

 

 

 Enterobacteriaceae

 

 

Enterobacteriaceae

 

Proteus, Providencia stuartii,

M.morganii subsp. sibonii

Serratia marcescens

 

Ciprofloxacin

 

 

Tetracycline

 

Tetracycline

yes______0.1-1 mg/l_______yes

 

 

 yes___________no__________yes

 

no____________no__________yes

<10%

When MIC > 0.1 mg/l all strains are resistant to nalidixic acid, MIC > MinHTML.htm ( L 27)

 

Resistant: MIC > 4 mg/l

(L 26)

 

(L 30, 31)